There’s another community for this: !localllama@sh.itjust.works
Though we mostly discuss the news and specific questions there, beginner questions are a bit more rare.
I think you already got a lot of good answers here, LMStudio, OpenWebUI, LocalAI…
I’d like to add KoboldCpp that’s kind of made for gaming/dialogue, but it can do everything. And from my experience it’s very easy to set up and bundles everything into one program.
Linux Antivirus is a very specific niche. It’s mostly there to scan for Windows viruses and malware. So your Linux mailserver for example (or storage system) filters those out before they appear on your employee’s computers.
What you’d instead do in Linux is harden your webserver and services, keep the webservices you host up to date and have some monitoring so you detect known rootkits or if your DNS server gets abused for a DDoS attack. And keep an eye on supply chain attacks if you’re a developer. Because that’s how attacks against Linux work. I’ve been scolded for saying this on Lemmy, but to this date, desktop computer malware isn’t really a thing with Linux. Attacks almost exclusively target webservers and Internet of Things devices, routers and so on.
So an Antivirus on a desktop computer isn’t going to do much, due to the lack of malware which works that way. And you’d still be vulnerable if someone hands you a malicious bash script to delete your home directory. It could however do something if you run Proton or Wine and run Windows programs in Linux.
If you want to do something for security, learn not to copy-paste stuff into the command line. Don’t run executables from random places of the internet. Try to rely on your distribution’s package repository. Do automatic updates, and generally do timely updates, especially with the webbrowser and stuff that’s reachable from outside. Set strong passwords. And don’t neglect your backups. Your harddisk is bound to fail anyway, eventually. I think that’s going to get you 99% of the way. Installing an antivirus is only the next 0.2%.